Greater Precision for Clear-Cut Results The appearance of vascular lesions can be significantly reduced by inducing selective photothermolysis of the hemoglobin and oxy-hemoglobin chromophores in the target tissue. This can be achieved using Dye-VL technology, a long-pulsed Nd:YAG laser, or a combination of both for optimal results. Deep leg veins are most effectively treated using the long-pulsed Nd:YAG laser.